Endocrine Abstracts

Introduction and Aim: Obesity is associated with an increased risk of hypothyroidism and chronic autoimmune thyroiditis (AIT). However, little is known about the underlying pathogenic mechanisms. Recently it has been evaluated the role played by sex hormones in the onset of AIT and, analysing the data from a large cohort of normal/overweight males, a positive correlation between an increased ratio of estradiol/testosterone levels (E2/T) and AIT was found. Since obese males are...

Objectives: AJCC/TNM staging system provides an estimate of mortality risk in differentiated thyroid cancer (DTC) patients and recent evidence showed that ATA risk stratification may improve the definition of this risk. We speculated that the integration of the response to the initial therapy (RIT) could better define the mortality risk.Methods: We retrospectively evaluated 891 consecutive DTC patients followed at the Section of Endocrinology, University...